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ERLEADA - Administration of 60 mg Tablets via a Feeding Tube

Last Updated: 07/16/2024

SUMMARY  

  • Johnson & Johnson cannot recommend any practices, procedures, or dosage administration techniques that deviate from the approved product labeling.
  • ERLEADA 60 mg is not commercially available as a solution or suspension.
  • For patients with a feeding tube, ERLEADA 60 mg tablets can be administered through a feeding tube 8 French or greater.1

ALTERNATE METHOD OF ADMINISTRATION

Administer 60 mg Tablets Through a Feeding Tube

ERLEADA 60 mg tablets (prescribed dose of 240 mg, 180 mg, or 120 mg) can be administered through a feeding tube 8 French or greater as follows1:

  1. Place the entire prescribed dose of ERLEADA tablets in the barrel of the syringe (use at least a 50 mL syringe) and draw up 20 mL of non-carbonated water into the syringe.
  2. Wait 10 minutes and then shake vigorously to disperse contents completely.
  3. Administer immediately through the feeding tube.
  4. Refill the syringe with non-carbonated water and administer. Repeat until no tablet residue is left in the syringe or feeding tube.

Literature Search

A literature search of MEDLINE®, Embase®, BIOSIS Previews®, and Derwent Drug File (and/or other resources, including internal/external databases) was conducted on 10 July 2024.

 

References

1 Data on File. Apalutamide. Company Core Data Sheet. Janssen Research & Development, LLC. EDMS-ERI-146013831; 2024.