Summary

• To avoid an incomplete administration of INVEGA TRINZA, ensure that the prefilled syringe is shaken vigorously for at least 15 seconds within 5 minutes prior to administration to ensure a homogeneous suspension and ensure the needle does not get clogged during injection.^1,2
• Always check the needle hub for signs of damage or leakage after attaching the needle to the syringe using a gentle twisting motion. A cracked needle hub can result in leakage of the medication and incomplete administration of the dose.²
• Slowly inject the entire contents of the syringe intramuscularly, deep into the selected deltoid or gluteal muscle of the patient. Do not administer by any other route.^1,2
• INVEGA TRINZA is a suspension, and the syringe is not calibrated. Therefore, in the event of an incomplete administration, there is no way to estimate how much of the dose is remaining in the syringe.
• In the event of an incompletely administered dose, do not re-inject the dose remaining in the syringe and do not administer another dose of INVEGA TRINZA. Closely monitor and treat the patient with oral supplementation as clinically appropriate until the next scheduled 3-month injection of INVEGA TRINZA.^1,2

LITERATURE SEARCH

A literature search of MEDLINE^®, Embase^®, BIOSIS Previews^®, and Derwent Drug File (and/or other resources, including internal/external databases) pertaining to this topic was conducted on 03 January 2025.