J&J Medical Connect
RYBREVANT®

(amivantamab-vmjw)

This information is intended for US patients and caregivers to access current scientific information about J&J Innovative Medicine products. It is prepared by Medical Information and is not intended to promote the use of our products, nor to provide medical advice.

What is the Dosing Schedule for RYBREVANT?

Last Updated: 01/29/2025

summary

Abbreviations: EGFR, epidermal growth factor receptor; Kg, kilogram; NSCLC, non-small cell lung cancer; TKI, tyrosine kinase inhibitor.
aRYBREVANT (amivantamab-vmjw) Prescribing Information.1
bThe recommended dose for patients with baseline body weight <80 kg and ≥80 kgs is 1050 mg and 1400 mg, respectively. Dose adjustment is not required for subsequent body weight changes.
cThe recommended dose for patients with baseline body weight <80 kg is 1400 mg (weekly for weeks 1 to 4) and 1750 mg (every 3 weeks starting at week 7 onwards). The recommended dose for patients with baseline body weight ≥80 kgs is 1750 mg (weekly for weeks 1 to 4) and 2100 mg (every 3 weeks starting at week 7 onwards). Dose adjustment is not required for subsequent body weight changes.
dYou will receive carboplatin every 3 weeks for up to 12 weeks.

PRODUCT LABELING

ADDITIONAL INFORMATION

This information is provided ONLY in response to your request and is not intended as medical advice, to promote the use of our product, or suggest using it in any manner other than as described in the PRESCRIBING INFORMATION. All decisions regarding your medical treatment should be made with your healthcare professional(s). Please contact your healthcare professional(s) to discuss the information in this response.

Please refer to the attached full PRESCRIBING INFORMATION and the PATIENT INFORMATION for RYBREVANT.1

References

1 RYBREVANT (amivantamab-vmjw) [Prescribing Information]. Horsham, PA: Janssen Biotech, Inc.;https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/RYBREVANT-pi.pdf