SUMMARY  

Here is a passage from the TREMFYA PEN INSTRUCTIONS FOR USE, which may be helpful to address your question:

Important Information You Need to Know Before Injecting TREMFYA Prefilled Pen (TREMFYA PEN)

• TREMFYA PEN comes in a single-dose Prefilled Pen containing one 200 mg dose.¹
• If your healthcare provider decides that you or a caregiver my be able to give your injections of TREMFYA PEN at home, you should receive training on the correct way to prepare and inject TREMFYA PEN before using it.¹
• Read the complete INSTRUCTIONS FOR USE before using your TREMFYA PEN and each time you get a new TREMFYA PEN. There may be new information. This information does not take the place of talking with your healthcare provider about your medical condition or treatment.¹
• Each TREMFYA PEN can only be used one time. Throw the used TREMFYA PEN away (see How Should I Dispose of TREMFYA PEN?) after one dose, even if there is still medicine left in it. Do not reuse your TREMFYA PEN.¹

How Should I Store TREMFYA PEN?

• Store in refrigerator between 36°F to 46°F (2°C to 8°C).¹
• Do not freeze your TREMFYA PEN.¹
• Do not shake your TREMFYA PEN.¹
• Keep your TREMFYA PEN and all medicines out of reach of children.¹
• Keep your TREMFYA PEN in the original carton to protect from light and physical damage.¹

How Should I Use TREMFYA PEN?

• Use TREMFYA exactly as your healthcare provider tells you to.¹
• You will need these supplies: 1 TREMFYA PEN, alcohol swabs, cotton balls or gauze pads, adhesive bandages, and a sharps container.¹
• Prepare for your injection as follows¹:
  • Inspect carton
    • Remove your TREMFYA PEN carton from the refrigerator and let it sit on a flat surface at room temperature for approximately 30 minutes before use.
    • Do not warm the TREMFYA PEN any other way.
    • Check the expiration date (“EXP”).
    • Do not use the TREMFYA PEN if the expiration date has passed or if the seal on the carton is broken. Contact your healthcare provider or pharmacist for a new TREMFYA PEN.
  • Inspect TREMFYA PEN
    • Check the liquid in the viewing window.
    • It should be clear and colorless to slightly yellow and may contain tiny white or clear particles. You may also see air bubbles. This is normal.
    • Do not inject if the liquid is cloudy, discolored, or has large particles. Call your healthcare provider or pharmacist for a new TREMFYA PEN.
  • Choose injection site
    • Select from the following areas for injection:
      • Front of thighs
      • Lower stomach area (lower abdomen), except for a 2-inch area right around your navel (belly-button)
      • Back of upper arms (only if someone else is giving you the injection)
    • Do not inject into skin that is tender, bruised, red, scaly, thick, or hard. Avoid areas with scars or stretch marks.
  • Clean injection site
    • Wash your hands well with soap and warm water.
    • Wipe your chosen injection site with an alcohol swab and allow it to dry.
    • Do not touch, fan, or blow on the injection site after you have cleaned it.
• Inject your TREMFYA PEN as follows¹:
  • Remove the cap when you are ready to inject
    • Do not touch the yellow needle guard. This may start the injection and you will not receive the dose.
    • Pull the cap straight off. It is normal to see a few drops of liquid.
    • Inject TREMFYA PEN within 5 minutes of removing the cap.
    • Do not put the cap back on as this may damage the needle.
    • Do not use your TREMFYA PEN if it is dropped after removing the cap. Call your healthcare provider or pharmacist for a new TREMFYA PEN.
  • Position TREMFYA PEN straight onto injection site then push and hold
    • Do not lift the TREMFYA PEN during injection. If you do, the yellow needle guard will lock and the full dose will not be delivered.
    • Position your TREMFYA PEN straight onto the injection site with the yellow needle guard against the skin and the viewing window facing you.
    • Press down on the TREMFYA PEN and keep holding it down against the skin.
    • You will hear the first click.
  • Keep holding your TREMFYA PEN firmly against the skin for about 10 seconds to hear a second click. You are almost done.
  • Confirm injection is complete
    • Keep holding firmly against the skin and confirm your injection is complete.
    • Your injection is complete when the plunger rod stops moving and fills the viewing window.
  • Lift straight up.
• After your injection, follow the steps below¹:
  • Check injection site
    • There may be a small amount of blood or liquid at the injection site. Gently hold pressure over the injection site with a cotton ball or gauze pad until any bleeding stops.
    • Do not rub the injection site. If needed, cover the injection site with a bandage.
  • Dispose of your TREMFYA PEN and cap
    • Put your used TREMFYA PEN and cap in an FDA-cleared sharps disposal container right away after use.
    • Do not throw away (dispose of) your TREMFYA PEN in your household trash.
    • Do not recycle your used sharps disposal container.

How Should I Dispose of TREMFYA PEN?

• If you do not have an FDA-cleared sharps disposal container, you may use a household container that is¹:
  • made of heavy-duty plastic
  • can be closed with a tight-fitting, puncture resistant lid, without sharps being able to come out
  • upright and stable during use
  • leak-resistant
  • properly labeled to warn of hazardous waste inside the container
• When your sharps disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of your sharps disposal container. There may be state or local laws about how you should throw away used needles and syringes.¹
• For more information about safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to the FDA’s website at: www.fda.gov/safesharpsdisposal. You may also consult your pharmacist.¹

ADDITIONAL INFORMATION

This information is provided ONLY in response to your request and is not intended as medical advice, to promote the use of our product, or suggest using it in any manner other than as described in the PRESCRIBING INFORMATION. All decisions regarding your medical treatment should be made with your healthcare professional(s). Please contact your healthcare professional(s) to discuss the information in this response.

Please refer to the attached full PRESCRIBING INFORMATION and the MEDICATION GUIDE for TREMFYA.¹