IMPORTANT INFORMATION ABOUT XARELTO

• XARELTO can cause bleeding which can be serious and may lead to death. During treatment with XARELTO, you are likely to bruise more easily, and it may take longer for the bleeding to stop. You may have a higher risk of bleeding if you take XARELTO and have certain other medical problems or take other medicines that increase your risk of bleeding. Please see the MEDICATION GUIDE for a list of other medications that increase your risk of bleeding and signs or symptoms of bleeding.¹
  • Call your doctor or get medical help right away if you or your child develop any signs or symptoms of bleeding.
• People who take a blood thinner medicine (anticoagulant) like XARELTO, and have medicine injected into their spinal and epidural area, or have a spinal puncture have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis). Please see MEDICATION GUIDE for a list of risk factors and symptoms of spinal or epidural blood clots.¹

summary

Here is a passage from the XARELTO MEDICATION GUIDE which may be helpful to address your question:

Can I take NSAIDs with XARELTO?

• You may have a higher risk of bleeding if you take XARELTO and take other medicines that increase your risk of bleeding, including¹:
  • Long-term (chronic) use of non-steroidal anti-inflammatory drugs (NSAIDs)
• People who take a blood thinner medicine (anticoagulant) like XARELTO, and have medicine injected into their spinal and epidural area, or have a spinal puncture have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis). Your risk of developing a spinal or epidural blood clot is higher if¹:
  • You take NSAIDs
• Tell your doctor if you take any of these medicines. Ask your doctor or pharmacist if you are not sure if your medicine is a NSAID.¹
• Call your doctor or get medical help right away if you or your child develop any of these signs or symptoms of bleeding¹:
  • Unexpected bleeding or bleeding that lasts a long time, such as:
    • Nose bleeds that happen often
    • Unusual bleeding from the gums
    • Menstrual bleeding that is heavier than normal or vaginal bleeding
  • Bleeding that is severe or you cannot control
  • Red, pink or brown urine
  • Bright red or black stools (looks like tar)
  • Cough up blood or blood clots
  • Vomit blood or your vomit looks like “coffee grounds”
  • Headaches, feeling dizzy or weak
  • Pain, swelling, or new drainage at wound sites

additional information

This information is provided ONLY in response to your request and is not intended as medical advice, to promote the use of our product, or suggest using it in any manner other than as described in the PRESCRIBING INFORMATION. All decisions regarding your medical treatment should be made with your healthcare professional(s). Please contact your healthcare professional(s) to discuss the information in this response.

Please refer to the attached full PRESCRIBING INFORMATION and the PATIENT MEDICATION GUIDE for XARELTO¹.