• Administered 5 weeks after the first injection.
• The recommended maintenance dose for treatment of schizophrenia is 117 mg. Some patients may benefit from lower or higher maintenance doses within the additional available strengths (39 mg, 78 mg, 156 mg, and 234 mg).
• There is no recommended monthly maintenance dose for patients with schizoaffective disorder; adjust dose based on tolerability and/or efficacy using available strengths. The 39 mg strength was not studied in the long-term schizoaffective disorder study.
• Adjustment of the maintenance dose may be made monthly. Adjust dose based on tolerability and/or efficacy using available strengths.
• To avoid a missed monthly dose, patients may be given the paliperidone palmitate injection up to 7 days before or after the monthly time point.
• The Prescribing Information does not encourage a reoccurring 3-week or 5-week cycle. There is no data to support the routine administration of INVEGA SUSTENNA maintenance doses at intervals shorter or longer than 4 weeks.
• When making dose adjustments, the prolonged-release characteristics of INVEGA SUSTENNA should be considered, as the full effect of the dose adjustment may not be evident for several months.

^aMonthly recommended dose